Logtalk runs on any operating-system with a standards compliant modern Prolog compiler. The interface between Logtalk and a specific backend Prolog compiler is accomplished using a small adapter file. The Logtalk distribution includes adapter files for all supported Prolog compilers:

Legacy Logtalk versions (2.x) provide support for some other Prolog compilers, which are no longer supported due to lack of compliance with official and de facto standards.